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Although GPX4 depletion alone failed to affect HSCs function in vivo , Vav1- Gpx4 knockout mice fed with a vitamin E-depleted diet exhibited a reduced number of HSCs and dysregulated hematopoiesis, mainly due to increased ferroptosis [22]

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In contrast, mirabegron is associated with moderate CYP2D6 inhibition, carries a hypertension warning, and must be swallowed whole